Ytan som är i kontakt med blod är täckt med Carmeda® Bioactive Surface (CBAS TM)för att minska trombrisken. Eftersom pumpen är transparent är det enkel att 

Ultra-smooth, flow-optimized blood contact surfaces with CARMEDA ® BioActive Surface* coating for the best possible blood compatibility Safe de-airing through de-airing port Blood pumps with tri-leaflet valves made of polyurethane and blood pumps with bileaflet valves made of carbon

The result is a proven thromoresistant surface with a long-term, safe clinical history. Because of its extensive publication history, there is emphasis on the CARMEDA ® BioActive Surface (CBAS ® Heparin Surface), a widely used commercialized technology for the covalent bonding of heparin. Begovac PC, Thomson RC, Fisher JL, Hughson A, Gällhagen A. Improvements in GORE-TEX ® Vascular Graft performance by Carmeda ® BioActive Surface heparin immobilization. European Journal of Vascular & Endovascular Surgery 2003;25(5):432-437.

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Begovac PC, Thomson RC, Fisher JL, et al. Improvements in GoreTex vascular graft performance by Carmeda bioactive surface heparin immobilization. Eur J Vasc Endovasc Surg. 2003;25:432-437. Heyligers JM, Verhagen HJ, Rotmans J, et al. Heparin immobilization reduces thrombogenicity of small caliber expanded polytetrafluoroethylene grafts.

graft surface, while the bioactive site remains free to interact with the blood to help prevent clotting.7 References 1. ®Begovac PC, Thomson RC, Fisher JL, Hughson A, Gällhagen A. Improvements in GORE-TEX Vascular Graft performance by Carmeda® BioActive Surface heparin immobilization. The CARMEDA ® BioActive Surface is a heparin-based coating designed to actively reduce thrombus formation on blood contacting medical devices.

The CARMEDA ® BioActive Surface is applied to a range of medical devices in our clean room. The facility includes ISO class 7 clean rooms and carefully controlled water and air supplies. This enables coating of Class III products according to both European and US requirements.

· Author information · Abstract · Full text links   The attempt to coat the artificial surfaces with heparin, an anticoagulant that imitates the 5.1.1 Medtronic Inc. (Carmeda Bioactive Surface®=CBAS). 13 Nov 2000 Use of the Carmeda BioActive Surface (CBAS) has been given approval by the Food and Drug Administration (FDA) in a pre-market approval  heparin (UFH) bound to its surface using a proprietary end point attachment mechanism (Carmeda BioActive Surface. [CBAS], Carmeda AB, Upplands Väsby;   17 Mar 2017 Cardiotomy Reservoir with Medtronic/Carmeda BioActive Surface) indicates the following similarities: • Intended Use: The intended use is the  Sweden)--the Carmeda BioActive Surface (CBAS)--has been coated onto Cordis 25 Clinical applications of the CBAS immobilized heparin surface include  The VIPER (Gore Viabahn Endoprosthesis with Heparin Bioactive Surface in the Flagstaff, AZ) with the Carmeda BioActive Surface (CBAS) coating (Upplands  9 May 2008 Medical devices featuring the Carmeda BioActive surface from Medtronic are being recalled because they are made with the contaminated  The CARMEDA® BioActive Surface is a heparin-based coating designed to actively reduce thrombus formation on blood contacting medical devices.

End-point covalent linkage of heparin to polymer surfaces was first made commercially available as Carmeda Bioactive SurfaceTM (Carmeda, Switzerland ), 

Figure 1: The GORE® VIABAHN® Endoprosthesis . External Nitinol Stent ePTFE Lining Ultra-smooth, flow-optimized blood contact surfaces with CARMEDA ® BioActive Surface* coating for the best possible blood compatibility Safe de-airing through de-airing port Blood pumps with tri-leaflet valves made of polyurethane and blood pumps with bileaflet valves made of carbon The CARMEDA ® BioActive Surface is applied to a range of medical devices in our clean room. The facility includes ISO class 7 clean rooms and carefully controlled water and air supplies. This enables coating The effects of carmeda bioactive surface on human blood components during simulated extracorporeal circulation. J Thorac Cardiovasc Surg . (1996) 111:1073–84.

Many scientific papers, including clinical studies, have demonstrated the safety, efficacy, and superiority of the CARMEDA ® BioActive Surface.
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External Nitinol Stent ePTFE Lining The general principle of the CARMEDA ® BioActive Surface technology is to attach functionally active heparin to the blood contacting surfaces of medical devices. Heparin is covalently bound to the surface by end-point attachment.

Below is a selection of currently approved products featuring the CARMEDA ® BioActive Surface. Berlin Heart EXCOR ® Ventricular Assist Device GORE ® PROPATEN ® Vascular Graft GORE ® VIABAHN ® Endoprosthesis GORE ® TIGRIS ® Vascular Stent The CARMEDA ® BioActive Surface (also known as CBAS ® Heparin Surface) is a mature technology with an impressive pre-clinical and clinical track record. Almost 700 global scientific reports have been published on the chemistry, biological properties, safety and clinical performance of the CARMEDA ® BioActive Surface technology. Follow the link below to find the updated CARMEDA ® BioActive The CARMEDA ® BioActive Surface is applied to a range of medical devices in our clean room.
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Berlin Heart EXCOR ® Ventricular Assist Device GORE ® PROPATEN ® Vascular Graft GORE ® VIABAHN ® Endoprosthesis GORE ® TIGRIS ® Vascular Stent The CARMEDA ® BioActive Surface is applied to a range of medical devices in our clean room.